St. Louis to Minneapolis Cruise Summary
The wildness of the Upper Mississippi is a realm where storybook towns combine with sweeping panoramas and deep-blue lakes, conjuring the works of Mark Twain.
From the Gateway Arch of St. Louis to the birthplace of Prince in Minneapolis, this cruise will take you to some of America’s most vibrant, bustling metropolises, each one filled with culture and landmarks, music, food and history.
In Hannibal, explore the Mark Twain Caves, where the author spent his childhood – or immerse yourself in the vintage cars and memorabilia of 20th-century America, at the Karlocks Kars & Pop Culture Museum.
Tour the Isabel Bloom sculpture studio in Davenport, followed by Iowa’s oldest city – Dubuque. See the Driftless landscapes surrounding La Crosse and get up-close and personal with America’s iconic Symbol of Freedom at the National Eagle Centre of Wabasha, near the picturesque red-brick city of Red Wing.
- Cruise through the stunning natural beauty of the Upper Mississippi region, the gateway to the American Midwest
- Discover the Mark Twain Caves, said to have been used by Jesse James as a hideout
- Tour the historic port city of Red Wing and go “nose to beak” with a bald eagle
2024 All-inclusive fares from £3,999 pp
Return scheduled flights from London
2-night Pre-cruise Hotel Stay+
Premium City Highlights Tour (Embarkation Day)+
Unlimited Included Guided Tours
Acclaimed Cuisine in Multiple Venues
In-room Dining Available
Bicycles* and Hiking Sticks
Live, Daily Onboard
Entertainment & Enrichment
Open Bars & Lounges
Port Taxes & Fees
*River Cruises Only
+1-night on Minneapolis -New Orleans and Snake & Columbia itineraries/No City Highlights Tour
Terms and Conditions
Lead in fares shown are to be used as a guide only, based on the lowest cabin category for two people sharing. Pricing may be subject to change based on flight pricing & availability. Other cabin categories are available. Single cabin grades are available on selected vessels and cabins for sole occupancy are available at a single supplement. All itineraries can be tailor-made to your specification with cruise only, additional hotel nights, flight upgrades and UK regional airport departures (subject to availability). Additional pre-voyage and post-voyage city stay packages (2 nights) may be purchased for an additional charge. Guests are required to present a credit card upon hotel check-in to cover their incidental charges. In lieu of an included pre-voyage hotel night on any voyage, a $50 per person onboard credit is available upon request and dependent upon voyage date. On a back-to-back voyage, two included hotel nights or a combination of one included hotel night plus a $50 per person onboard credit will be granted in lieu of taking a second included hotel night. All fares, itineraries, hotels, entertainment, shore excursions and other voyage attributes are subject to change, and we are not responsible for errors or omissions therein. American Queen Voyages is represented in the UK & Europe by Light Blue Travel (ABTA D6183 & V9324 ATOL 5489). Full Booking Conditions.